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br Spatial working memory is GluR
2022-01-03

Spatial working memory is GluR-A-dependent The radial maze task also allowed us to study hippocampus-dependent spatial working memory. On spatial working memory tasks, the correct spatial response that the animal must make varies from trial to trial and is dependent on some conditional, trial-spe
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Given the proposed importance of conformational dynamics to
2022-01-03

Given the proposed importance of conformational dynamics to GCK's allosteric regulation, a number of biophysical methods have been utilized to probe the enzyme's dynamic structural landscape. Investigations into the mechanism of concentration equation binding, using changes in the enzyme's intrinsi
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br During cardiac ischaemia a decrease in GJ coupling
2022-01-03

During cardiac ischaemia, a decrease in GJ coupling is observed, which results in slower conduction of electrical impulses and a higher risk of arrhythmias.[13], [20] In Huntington’s disease an increase in the mao inhibitors list of 5 Cxs was observed in the astrocytes in the brain, suggesting an
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DNAzymes a series of nucleotide sequences with specific cata
2022-01-03

DNAzymes, a series of nucleotide sequences with specific catalytic activity, have been reported frequently applied in detection assays for such as ions and amino acids, due to the advantage in stability, high cost-effectiveness and modification convenience, by comparison with protein enzymes. The DN
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br Conclusion In summary a series of novel
2022-01-03

Conclusion In summary, a series of novel GPR40 agonists bearing phenylpropiolic sitagliptin phosphate motif with favorable metabolic stability were prepared and evaluated for their activities as GPR40 agonists. Among them, compound 9 was identified as a structurally distinct GPR40 agonist possess
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br Conclusion br Acknowledgements This study was
2022-01-03

Conclusion Acknowledgements This study was supported by the China Postdoctoral Science Foundation (No.2015M581817), the National Research Council of Science and Technology Support Program (2015BAD03B05-06), and the Priority Academic Program Development of Jiangsu Higher Education Institutions
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