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br Methods br Results br Discussion Chronic
2022-12-02
Methods Results Discussion Chronic stress renders individuals vulnerable to diseases, and this effect might be, at least partially, mediated by stress hormone-induced immunosuppression. Therefore, investigating the effects of catecholamines on immune nearly is of high relevance. We hypothe
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AdipoR and AdipoR have been
2022-12-02
AdipoR1 and AdipoR2 have been reported to be present in almost all type of tissues and low cl 2 levels have been observed in white adipose tissue (Inukai et al., 2005). These receptors have been observed to become deregulated with the onset of obesity, resulting in a reduced level of APN expression
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In previous research we determined that blocking mAC during
2022-12-02
In previous research, we determined that blocking mAC during heparin-induced capacitation result in sperm having a lesser oxygen consumption, suggesting that cAMP produced by this enzyme would be linked to mitochondrial activity and, therefore, with the regulation of sperm metabolism (Fernández and
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br Acknowledgments This work was supported by the R D
2022-12-02
Acknowledgments This work was supported by the R&D Program of the Institutional Research Program of KRICT (SI1701-02), and by the Next generation carbon upcycling project of Ministry of Science and ICT. JSC is kindly grateful to the National Research Council of Science and Technology (NST) for fi
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The relatively high concentration of HT used in this study
2022-12-02
The relatively high concentration of 5-HT used in this study (100 µM) is consistent with the concentrations used in other published ex vivo studies (Ropert and Guy, 1991, Passani et al., 1994, Shen and Andrade, 1998). In our paradigm 5-HT was focally applied at the surface of the slice via a fast pe
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CGP 55845 hydrochloride Preliminary results of studies spons
2022-12-02
Preliminary results of studies sponsored by the manufacturer of ETC-1002 have also shown positive results for monotherapy in statin-intolerant patients and for the combined use of the ACL inhibitor plus other cholesterol-reducing agents. In patients with a documented history of intolerance to statin
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In considering the roles of these enzymes in normal physiolo
2022-12-02
In considering the roles of these enzymes in normal physiology, given the importance of GLUT4-dependent glucose uptake and glucose-dependent fatty bepridil synthesis for systemic metabolic homeostasis (Herman and Kahn, 2006, Herman et al., 2012), deletion of Acly in adipocytes results in a surprisi
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Functional enhancers are often composed of binding motifs
2022-12-02
Functional enhancers are often composed of binding motifs of multiple key transcription factors to confer spatial and temporal regulation of genes in a certain context. In the uterus, the difference between the number of genes that have associated PGR occupancy and that of progesterone responsive ge
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Knowledge about adipose tissue has evolved considerably over
2022-12-02
Knowledge about adipose tissue has evolved considerably over the last two decades. Always been described as an inert tissue having the function of stocking lipids, adipose tissue is now recognized as a real organ with both metabolic and endocrine functions secreting various factors into the blood to
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br Drugs with documented pro apoptotic effects on platelets
2022-12-02
Drugs with documented pro-apoptotic effects on platelets More than 200 drugs are reported to cause thrombocytopenia [5,42]. The concept of platelet apoptosis is relatively new and was only recently evaluated in the context of drug-induced thrombocytopenia [43]. Table 2 lists the drugs presently k
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Additional support for a role of HMGN in
2022-12-02
Additional support for a role of HMGN1 in enhancing DNA repair comes from studies of transcription-coupled repair (TCR) in human cells. Lesions in the template strand of DNA induced by UV light stall the movement of RNA polymerase II (RNAPII) and interrupt transcription. Removal of these transcripti
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br Methodology br Antibiotics in lakes br Antibiotic resista
2022-12-02
Methodology Antibiotics in lakes Antibiotic resistance genes in lakes Perspectives of study on Fmoc-Asp-OAll and ARGs in lakes Conclusion This paper systematically reviewed the distribution of antibiotics and ARGs in global lakes. A total of 57 antibiotics reported at least once in t
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Previous studies to investigate the functions of AHR in Treg
2022-12-01
Previous studies to investigate the functions of AHR in Treg Spermine NONOate have employed a loss-of-function approach, using AHR complete-null mice, or a gain-of-function approach by ligand administration. However, these approaches may confound the interpretation of the results. For example, the
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Voluminous literature about the neuroendocrine mechanism
2022-12-01
Voluminous literature about the neuroendocrine mechanism of reproduction and energy regulation has emerged from studies involving mammalian species. The avian infundibular nucleus (equivalent structure to the mammalian arcuate nucleus) consists of two neuronal populations, one of which expresses neu
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salbutamol sulfate Since natural and recombinant glycoprotei
2022-12-01
Since natural and recombinant glycoprotein hormones exhibit some differences in their carbohydrate structures, we checked whether this could affect the permissive effect on FSK-induced cyclic AMP response in MLTC-1 cells. Fig. 6 shows that the same sensitizing effect to FSK is observed with pituitar
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