• There have been a few

  2021-11-25

  

  There have been a few studies investigating the effects of histamine on mast cells but the majority of these has been on rodent and cultured mast cells (Hofstra et al., 2003, Lippert et al., 2004, Jemima et al., 2014). How representative these systems are of primary human cells is a moot point since

• br Materials and methods br Results To examine the

  2021-11-25

  

  Materials and methods Results To examine the time and organ specific effect of normal photoperiod and dark environment on the gw501516 australia of different SlHXKs and on the enzyme activities, these parameters were determined in different leaf positions of tomato plants. Under control condi

• br Materials and methods br Results br Discussion CRC and

  2021-11-25

  

  Materials and methods Results Discussion CRC and PC occupy a good share in cancer-related deaths worldwide. CRC is a common gastrointestinal malignancy with a growing incidence whereas PC is one of the most dreadful malignancies with extremely poor survival rates. Though over the past decad

• Whereas Sororin is dispensable in the absence of

  2021-11-25

  

  Whereas Sororin is dispensable in the absence of Wapl [14], overexpressed Haspin only partly supports cohesion in Sororin-depleted cells. Thus, although Haspin and Sororin have functional similarities, they are not fully redundant at the centromere. Haspin may have a mitosis-specific role in maintai

• br Materials and methods br Results

  2021-11-24

  

  Materials and methods Results Discussion In this study, we demonstrated that zaprinast (a cGMP-PDE inhibitor) induced the intracellular calcium mobilization in the tetracaine hydrochloride coexpressing GPR35 and Gqi5, Gqo5, or Gα16. Induction of intracellular calcium mobilization by zaprina

• In summary through medicinal chemistry design and computer

  2021-11-24

  

  In summary, through medicinal chemistry design and computer-assisted conformational modeling, the initial lead was evolved into a series of dihydrobenzofuran derivatives, , as potent GPR119 agonists. Optimization of general structure at various regions of the molecule, including the substituent on

• Introduction Carbohydrates are some of the most stereochemic

  2021-11-24

  

  Introduction Carbohydrates are some of the most stereochemically complex biological molecules found in nature. In addition to their energetic and structural roles in living systems, their role when covalently linked to proteins is critically important in a myriad of molecular recognition processes.

• The main results whose proofs

  2021-11-24

  

  The main results, whose proofs depend on the explicit calculation of , include To set our work into the historical context, we note that the transporter category algebras are skew group algebras, and thus are fully group-graded algebras. This work is partially motivated by the papers on fully group

• Dynorphin (2-17), amide, porcine australia In order t http w

  2021-11-24

  

  In order to validate the correctness of our interpretation of the gap-FRAP data and the analysis of GJC in astrocytes, we used a mathematical model based on morphological and experimental data. This mathematical model is based on SR101 diffusion in an elementary network. In agreement with the morpho

• br Pannexins which form channels connecting

  2021-11-24

  

  Pannexins, which form channels connecting NPPB with the extracellular environment, have also been studied in the setting of NASH. When open these channels participate in inflammatory processes. A decrease in lobular inflammation and oxidative stress was observed in mice with pannexin deletion. Ho

• These observations are of particular interest

  2021-11-24

  

  These observations are of particular interest in the context of recent conceptual changes regarding the mechanisms by which different types of leukocytes contribute to atherogenesis. Over the last decade, the paradigm of the predominant circulatory origin of lesional macrophages has been challenged

• br Discussion and concluding remarks FPR is considered

  2021-11-24

  

  Discussion and concluding remarks FPR1 is considered to be a promising drug target for treating inflammatory and immunological diseases. Thus, natural compounds that could block and/or regulate FPR1 activity may be an important source of novel therapeutics for modulating inflammatory processes. H

• Introduction Terpenoids also known as isoprenoids constitute

  2021-11-24

  

  Introduction Terpenoids, also known as isoprenoids, constitute a large family of natural products comprising at least 22,000 compounds and play diverse and important roles in plants as hormones, phytosynthetic pigments, and electron carriers [1], [2]. In addition, volatilized terpenoids contribute

• StemRegenin 1 br Neurodystrophic effects of HO

  2021-11-24

  

  Neurodystrophic effects of HO-1 It is well known that neonatal hyperbilirubinemia (jaundice) may lead to irreversible neurological injury in children (kernicterus). This outcome can be prevented by photodegradation of circulating bilirubin or treatment with metalloporphyrin inhibitors of HO enzym

• br Hedgehog in chronic liver disease The liver responds

  2021-11-24

  

  Hedgehog in chronic liver disease The liver responds to different chronic insults with a highly conserved wound healing response during which different cell types must communicate to reconstruct fully functional, healthy liver parenchyma. The inter-cellular dialogue that orchestrates effective li

14236 records 527/950 page Previous Next First page 上5页 526527528529530 下5页 Last page